Mitochondria Initiate and Regulate Sarcopenia.
نویسندگان
چکیده
We present the hypothesis that an accumulation of dysfunctional mitochondria initiates a signaling cascade leading to motor neuron and muscle fiber death and culminating in sarcopenia. Interactions between neural and muscle cells that contain dysfunctional mitochondria exacerbate sarcopenia. Preventing sarcopenia will require identifying mitochondrial sources of dysfunction that are reversible.
منابع مشابه
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عنوان ژورنال:
- Exercise and sport sciences reviews
دوره 45 2 شماره
صفحات -
تاریخ انتشار 2017